Demelan 3 in 1 Combination For Hyperpigmentation
Demelan is a depigmenting cream with 3 active ingredients, i.e. alpha-arbutin, kojic acid and glycolic acid. Alpha-arbutin is derived from the leaves of bearberry, cranberry or mulberry shrubs. It inhibits the production of melanin and is better tolerated than hydroquinone, an ingredient found in other depigmenting creams. Kojic acid is a by-product in the fermentation process of malting rice and also inhibits the production of melanin. Glycolic acid is a peeling agent that assists the outer skin to shed, which improves the appearance and texture of the skin.
What is hyperpigmentation?
Hyperpigmentation, or dark discolouration of the skin, is a common and distressing condition that is difficult to treat, particularly in darker skin. Hyperpigmentation can be divided into two types, i.e. inflammatory and non-inflammatory. Inflammatory hyperpigmentation is caused by various inflammatory skin disorders, e.g. acne, eczema and contact dermatitis. Melasma is a common form of noninflammatory hyperpigmentation. The aim of this leaflet is to provide information on the diagnosis, treatment and prevention of melasma.
What is melasma?
Melasma is dark skin discolouration (hyperpigmentation) that appears on the sun-exposed areas of the face. It happens when melanocytes in the skin increase their production of a pigment called melanin. Without treatment, melasma can persist for months or years.
What are the symptoms?
Irregular patches of brown colour are commonly seen over the cheeks, forehead, nose, upper lip or chin, usually in a symmetrical fashion. Although melasma is cosmetic, it is nonetheless a source of stress and embarrassment for the person affected.
What causes melasma?
Sun exposure is a precipitating factor for melasma.2 Melasma is often associated with the female hormone oestrogen. It is common in pregnant women, women who are taking birth control pills (oral contraceptives) and women taking hormone replacement therapy (HRT) during menopause. Certain medications, such as anti-epileptic drugs, have also been implicated. Melasma of the upper lip is frequently reported in women who wax this area for hair removal.
A topical depigmenting cream (a cream that reduces pigment) is recommended as first-line treatment. The Pigmentary Disorders Academy (PDA) recommends the use of topical creams with at least THREE active ingredients. As a general recommendation, treatment must be continued for several months before benefits will be seen. Second-line treatments include chemical peels and laser treatments.
How to use Demelan
- Apply small quantities every second day for the first week
- Apply preferably in the evening after the skin cleaning regimen
- Avoid applying to eyelids, external corners of the mouth or nose, or injured or irritated skin
- Avoid prolonged sun exposure while using Demelan
- Use in combination with a broad spectrum sunscreen of at least SPF 15 and continue for a week after discontinuation of Demelan
Tips for successful treatment
• Avoiding the sun and using sunscreen are key to preventing melasma and ensuring successful treatment.
• Protect your face by wearing a hat when you are outside.
• It is advisable to use a broad-spectrum sunscreen that blocks UVA as well as UVB rays with a sun protection factor (SPF) of 30 or higher.
• Sunscreens containing physical blockers, e.g. titanium dioxide and zinc oxide are generally preferred over chemical blockers because of their broader protection.
• Remember that UVA rays can penetrate ordinary glass, therefore sunscreen needs to be worn even while you are indoors or driving a car.
• Speak to your doctor about switching to a non-hormonal form of birth control if you are using hormonal methods.
Speak to your healthcare professional and/ or refer to the Demelan package insert for further information.
Unmask your natural beauty with Demelan – 3 in 1 Depigmenting cream
With Alpha-arbutin, Kojic Acid and Glycolic Acid.
Do you need more information about Demelan? Contact Glenmark Pharma South Africa today! Demelan is also available in Pharmacies from R175.